Title | ||
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Thalamus parcellation using multi-modal feature classification and thalamic nuclei priors. |
Abstract | ||
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Segmentation of the thalamus and thalamic nuclei is useful to quantify volumetric changes from neurodegenerative diseases. Most thalamus segmentation algorithms only use T1-weighted magnetic resonance images and current thalamic parcellation methods require manual interaction. Smaller nuclei, such as the lateral and medial geniculates, are challenging to locate due to their small size. We propose an automated segmentation algorithm using a set of features derived from diffusion tensor image (DTI) and thalamic nuclei location priors. After extracting features, a hierarchical random forest classifier is trained to locate the thalamus. A second random forest classifies thalamus voxcls as belonging to one of six thalamic nuclei classes. The proposed algorithm was tested using a leave-one-out cross validation scheme and compared with state-of-the-art algorithms. The proposed algorithm has a higher Dice score compared to other methods for the whole thalamus and several nuclei. |
Year | DOI | Venue |
---|---|---|
2016 | 10.1117/12.2216987 | Proceedings of SPIE |
Keywords | Field | DocType |
Diffusion MRI,magnetic resonance imaging,machine learning,segmentation,thalamus parcellation | Thalamus,Voxel,Computer vision,Diffusion MRI,Segmentation,Image segmentation,Artificial intelligence,Prior probability,Random forest,Cross-validation,Physics | Conference |
Volume | ISSN | Citations |
9784 | 0277-786X | 2 |
PageRank | References | Authors |
0.37 | 8 | 5 |
Name | Order | Citations | PageRank |
---|---|---|---|
Jeffrey Glaister | 1 | 20 | 3.46 |
Aaron Carass | 2 | 383 | 43.15 |
Joshua Stough | 3 | 24 | 3.72 |
Peter A. Calabresi | 4 | 232 | 20.40 |
Jerry L. Prince | 5 | 4990 | 488.42 |