Title
Finding Nonlinear Relationships in fMRI Time Series with Symbolic Regression.
Abstract
The brain is an intrinsically nonlinear system, yet the dominant methods used to generate network models of functional connectivity from fMRI data use linear methods. Although these approaches have been used successfully, they are limited in that they can find only linear relations within a system we know to be nonlinear. This study employs a highly specialized genetic programming system which incorporates multiple enhancements to perform symbolic regression, a type of regression analysis that searches for declarative mathematical expressions to describe relationships in observed data. Publicly available fMRI data from the Human Connectome Project were segmented into meaningful regions of interest and highly nonlinear mathematical expressions describing functional connectivity were generated. These nonlinear expressions exceed the explanatory power of traditional linear models and allow for more accurate investigation of the underlying physiological connectivities.
Year
DOI
Venue
2016
10.1145/2908961.2909021
GECCO (Companion)
Keywords
Field
DocType
Symbolic regression, Computational neuroscience, Functional magnetic resonance imaging, Nonlinear relationships
Human Connectome Project,Nonlinear system,Expression (mathematics),Regression analysis,Linear model,Computer science,Genetic programming,Artificial intelligence,Symbolic regression,Machine learning,Network model
Conference
Citations 
PageRank 
References 
1
0.38
1
Authors
2
Name
Order
Citations
PageRank
James Hughes1144.55
Mark Daley216622.18