Title
Apoptosis in Cancer Cells.
Abstract
Programmed cell death changes and loss of cell growth and anti-growth regulation signals may result in uncontrolled cell proliferation, disorganized tissue growth and tumor formation. Malignant solid tumors, i.e. lung and brain tumors, are one of the most common and the most serious diseases nowadays and therefore considered a major issue in modern medicine. Despite intensive progress in cancer research, the survival rate of patients with diagnosed malignant solid tumors hasn't improved significantly. Radiotherapy and chemotherapy work predominantly by inducing apoptosis. The purpose of this article is to describe the role of apoptosis and to review currently known agents that allow induction of apoptosis in cancer cells. The identification of potential new targets for tumor treatment and processes in altered tumor cell metabolism is the challenging area of research. Recognizing the attributes of malignant tumor growth inhibition may help in the development of novel treatment strategies.
Year
DOI
Venue
2016
10.1007/978-3-319-39904-1_18
INFORMATION TECHNOLOGIES IN MEDICINE (ITIB 2016), VOL 2
Keywords
Field
DocType
Apoptosis,Cancer,Solid tumor,Apoptotic inhibitors
Cancer cell,Chemistry,Cancer research,Apoptosis,Fas ligand,Antisense DNA,Fas receptor
Conference
Volume
ISSN
Citations 
472
2194-5357
0
PageRank 
References 
Authors
0.34
0
5
Name
Order
Citations
PageRank
Eva Blahovcová100.34
Henrieta Skovierová200.34
Ján Strnádel300.34
Dusan Mistuna400.34
Erika Halasová500.34