Title
CAFÉ-Map: Context Aware Feature Mapping for mining high dimensional biomedical data.
Abstract
Feature selection and ranking is of great importance in the analysis of biomedical data. In addition to reducing the number of features used in classification or other machine learning tasks, it allows us to extract meaningful biological and medical information from a machine learning model. Most existing approaches in this domain do not directly model the fact that the relative importance of features can be different in different regions of the feature space. In this work, we present a context aware feature ranking algorithm called CAFÉ-Map. CAFÉ-Map is a locally linear feature ranking framework that allows recognition of important features in any given region of the feature space or for any individual example. This allows for simultaneous classification and feature ranking in an interpretable manner. We have benchmarked CAFÉ-Map on a number of toy and real world biomedical data sets. Our comparative study with a number of published methods shows that CAFÉ-Map achieves better accuracies on these data sets. The top ranking features obtained through CAFÉ-Map in a gene profiling study correlate very well with the importance of different genes reported in the literature. Furthermore, CAFÉ-Map provides a more in-depth analysis of feature ranking at the level of individual examples.
Year
DOI
Venue
2016
10.1016/j.compbiomed.2016.10.006
Computers in Biology and Medicine
DocType
Volume
ISSN
Journal
79
0010-4825
Citations 
PageRank 
References 
1
0.35
0
Authors
3
Name
Order
Citations
PageRank
Fayyaz ul Amir Afsar Minhas1279.37
Amina Asif255.51
Muhammad Arif326645.68