Title
A method for predicting protein complex in dynamic PPI networks.
Abstract
We construct four dynamic PPI networks, and accurately predict many well-characterized protein complexes. The experimental results show that (i) the dynamic active information significantly improves the performance of protein complex prediction; (ii) our method can effectively make good use of both the dynamic active information and the topology structure information of dynamic PPI networks to achieve state-of-the-art protein complex prediction capabilities.
Year
DOI
Venue
2016
10.1186/s12859-016-1101-y
BMC Bioinformatics
Keywords
Field
DocType
Positive Predictive Value, Predict Protein Complex, Protein Complex Prediction, Active Time Point, Integrate Gene Expression Data
Protein Interaction Map,Protein–protein interaction,Computer science,Transcriptome,Systems biology,Artificial intelligence,Bioinformatics,Computational biology,DNA microarray,Machine learning
Journal
Volume
Issue
ISSN
17
S-7
1471-2105
Citations 
PageRank 
References 
5
0.40
11
Authors
6
Name
Order
Citations
PageRank
Yijia Zhang111314.67
Hongfei Lin2768122.52
Zhihao Yang327036.04
Jian Wang411218.98
Yiwei Liu550.40
Shengtian Sang6142.95