Title
Identification of gene-drug interactions that impact patient survival in TCGA.
Abstract
While the pipeline produced several possible interactions where increased survival is linked to normal or increased copy number of a given gene for patients treated with a given drug, no instance of low copy number or full deletion was linked to increased survival. The development of this pipeline shows a promising utility to identify possible beneficial gene-drug interactions that could improve patient survival and may illustrate some of the problems inherent in this kind of analysis on these data.
Year
DOI
Venue
2016
10.1186/s12859-016-1255-7
BMC Bioinformatics
Keywords
Field
DocType
Gene-drug interaction,Survival,TCGA
Biological data,Disease,Survival rate,Biology,Copy-number variation,Glioma,Bioinformatics,Survival analysis,Genetics,Cancer,DNA microarray
Journal
Volume
Issue
ISSN
17
1
1471-2105
Citations 
PageRank 
References 
1
0.65
0
Authors
2
Name
Order
Citations
PageRank
John Christian Givhan Spainhour131.74
Peng Qiu2476.73