Title
A Fast Eulerian Approach for Computation of Global Isochrons in High Dimensions.
Abstract
We present a novel Eulerian numerical method to compute global isochrons of a stable periodic orbit in high dimensions. Our approach is to formulate the asymptotic phase as a solution to a first order boundary value problem and solve the resulting Hamilton-Jacobi equation with the parallel fast sweeping method. All isochrons are then given as isocontours of the phase. We apply this method to the Hodgkin-Huxley equations and a model of a dopaminergic neuron which exhibits mixed mode oscillations. Our results show that this Eulerian scheme is an efficient, accurate method for computing the asymptotic phase of a periodic dynamical system. Furthermore, by computing the phase on a Cartesian grid, it is simple to compute the gradient of phase, and thus compute an "almost phaseless" target set for the purposes of desynchronization of a system of oscillators.
Year
DOI
Venue
2016
10.1137/140998615
SIAM JOURNAL ON APPLIED DYNAMICAL SYSTEMS
Keywords
Field
DocType
isochrons,neuron models,mixed mode oscillation (MMO),desynchronization,Hamilton-Jacobi,parallel,high dimensions
Boundary value problem,Oscillation,Regular grid,Mathematical analysis,Eulerian path,Numerical analysis,Periodic graph (geometry),Mathematics,Dynamical system,Computation
Journal
Volume
Issue
ISSN
15
3
1536-0040
Citations 
PageRank 
References 
2
0.36
11
Authors
4
Name
Order
Citations
PageRank
Miles Detrixhe1231.72
Marion Doubeck220.36
Jeff Moehlis327634.17
Frédéric Gibou485064.05