Paper Info
Title
Differences in continuous spectra of fractionated electrograms in paroxysmal versus persistent atrial fibrillation.
Abstract
IntroductionQuantitative measurements are helpful to discern fractionated electrograms in paroxysmal and persistent atrial fibrillation (AF), and may be useful to detect optimal ablation sites. However, electrical activation events can be transient, leading to erroneous estimates of electrogram properties. Measurement of continuous changes in electrogram frequency content may improve analysis. MethodFractionated local electrograms from 10 paroxysmal and 10 persistent AF patients were acquired from outside the pulmonary vein ostia and left atrial free wall using the distal bipolar ablation catheter electrode, and analyzed over continuous 16 second intervals. A New Spectral Estimator (NSE) updated the frequency spectrum and spectral parameters once per millisecond. The tallest spectral peak (dominant frequency or DF) was determined. Statistical tests of variability were used to determine significant differences between paroxysmal and persistent AF. ResultsChanges in the value of the DF over 16 seconds were caused by transient drifts in the frequency of the dominant peak, or by changes in which peak had the highest amplitude. The continuous DF and the spectral profile parameters were more highly variable in paroxysmal as compared with persistent AF patients (p
Year
DOI
Venue
2016
10.1016/j.compbiomed.2016.06.021
Comp. in Bio. and Med.
Keywords
Field
DocType
Atrial fibrillation,Dominant frequency,Paroxysmal,Persistent,Power spectrum
Atrial fibrillation,Continuous spectrum,Dominant frequency,Internal medicine,Cardiology,Ablation,Spectral density,Frequency spectrum,Amplitude,Medicine,Pulmonary vein
Journal
Volume
Issue
ISSN
76
C
0010-4825
Citations 
PageRank 
References 
1
0.48
1
Authors
4
Name
Order
Citations
PageRank
Edward J. Ciaccio116530.79
Angelo B. Biviano273.13
Vivek Iyer3435.57
Hasan Garan4157.97