Title
Development of Microfluidic Systems Enabling High-Throughput Single-Cell Protein Characterization.
Abstract
This article reviews recent developments in microfluidic systems enabling high-throughput characterization of single-cell proteins. Four key perspectives of microfluidic platforms are included in this review: (1) microfluidic fluorescent flow cytometry; (2) droplet based microfluidic flow cytometry; (3) large-array micro wells (microengraving); and (4) large-array micro chambers (barcode microchips). We examine the advantages and limitations of each technique and discuss future research opportunities by focusing on three key performance parameters (absolute quantification, sensitivity, and throughput).
Year
DOI
Venue
2016
10.3390/s16020232
SENSORS
Keywords
Field
DocType
high-throughput,single-cell analysis,microfluidics,protein characterization
Nanotechnology,Analytical chemistry,Microfluidics,Engineering,Single-cell analysis,Throughput,Barcode
Journal
Volume
Issue
ISSN
16
2
1424-8220
Citations 
PageRank 
References 
0
0.34
1
Authors
6
Name
Order
Citations
PageRank
Beiyuan Fan100.34
Xiufeng Li200.34
Deyong Chen31310.49
Hongshang Peng400.34
Junbo Wang55416.41
Jian Chen62315.42