Name
Abstract | ||
|---|---|---|
An abdominal aortic aneurysm (AAA) is an enlargement of the abdominal aorta which, if left untreated, can progressively widen and may rupture with fatal consequences. In this paper, we determine an optimal treatment policy using Markov decision process modeling. The policy is optimal with respect to the number of quality adjusted life-years (QALYs) that are expected to be accumulated during the remaining life of a patient. The new policy takes into account factors that are ignored by the current clinical policy (e.g. the life-expectancy and the age-dependent surgical mortality). The resulting optimal policy is structurally different from the current policy. In particular, the policy suggests that young patients with small aneurysms should undergo surgery. The robustness of the policy structure is demonstrated using simulations. A gain in the number of expected QALYs is shown, which indicates a possibility of improved care for patients with AAAs. |
Year | DOI | Venue |
|---|---|---|
2016 | 10.1109/CCA.2016.7587869 | 2016 IEEE Conference on Control Applications (CCA) |
Keywords | DocType | Volume |
Abdominal aortic aneurysm (AAA),biosystems,decision making,Markov decision process (MDP),public healthcare,treatment policy | Journal | abs/1611.02177 |
ISSN | ISBN | Citations |
1085-1992 | 978-1-5090-0756-1 | 0 |
PageRank | References | Authors |
0.34 | 3 | 4 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Robert Mattila | 1 | 4 | 3.51 |
| Antti Siika | 2 | 0 | 0.34 |
| Joy Roy | 3 | 0 | 0.34 |
| Bo Wahlberg | 4 | 210 | 40.68 |