Title
An adaptive weighted degree kernel to predict the splice site
Abstract
The weighted degree kernel is a good means to predict the splice site. Its prediction performance is affected by positions in the DNA sequence of nucleotide bases. Based on this fact, we propose confusing positions in this article. Using the confusing positions and the key positions which we proposed in previous work, we construct a weight array to obtain adaptive weighted degree kernel, a kind of string kernel to predict the splice site. Then to prove the efficient and advance of the method, we use the public available dataset to train support vector machines to compare the performance of the adaptive weighted degree kernel and conventional weighted degree kernel. The results show that the adaptive weighted degree kernel has better performance than the weighted degree kernel. © Springer International Publishing AG 2016.
Year
DOI
Venue
2016
10.1007/978-3-319-46654-5_81
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Keywords
Field
DocType
Splice site prediction,Adaptive weighted degree kernel,Confusing positions,Weight array,Support vector machine
Kernel (linear algebra),Computer science,Support vector machine,Algorithm,RNA splicing,String kernel
Conference
Volume
ISSN
Citations 
9967 LNCS
0302-9743
0
PageRank 
References 
Authors
0.34
6
4
Name
Order
Citations
PageRank
Wang Tianqi100.34
Yan Ke200.68
Xu Yong3211973.51
Liu Jin-Xing44016.11