Title
Multi-label Deep Regression and Unordered Pooling for Holistic Interstitial Lung Disease Pattern Detection.
Abstract
Holistically detecting interstitial lung disease (ILD) patterns from CT images is challenging yet clinically important. Unfortunately, most existing solutions rely on manually provided regions of interest, limiting their clinical usefulness. In addition, no work has yet focused on predicting more than one ILD from the same CT slice, despite the frequency of such occurrences. To address these limitations, we propose two variations of multi-label deep convolutional neural networks (CNNs). The first uses a deep CNN to detect the presence of multiple ILDs using a regression-based loss function. Our second variant further improves performance, using spatially invariant Fisher Vector encoding of the CNN feature activations. We test our algorithms on a dataset of 533 patients using five-fold cross-validation, achieving high area-under-curve (AUC) scores of 0.982, 0.972, 0.893 and 0.993 for Ground Glass, Reticular, Honeycomb and Emphysema, respectively. As such, our work represents an important step forward in providing clinically effective ILD detection.
Year
DOI
Venue
2016
10.1007/978-3-319-47157-0_18
Lecture Notes in Computer Science
Keywords
DocType
Volume
Interstitial lung disease detection,Convolutional neural network,Multi-label deep regression,Unordered pooling,Fisher vector encoding
Conference
10019
ISSN
Citations 
PageRank 
0302-9743
3
0.44
References 
Authors
14
6
Name
Order
Citations
PageRank
Mingchen Gao157925.95
Ziyue Xu259735.50
Le Lu3129786.78
Adam P. Harrison410117.06
ronald m summers540014.10
Daniel J. Mollura630.44