Name
Title | ||
|---|---|---|
Language-related cerebral oscillatory changes are influenced equally by genetic and environmental factors. |
Abstract | ||
|---|---|---|
Twin studies have suggested that there are genetic influences on inter-individual variation in terms of verbal abilities, and candidate genes have been identified by genome-wide association studies. However, the brain activities under genetic influence during linguistic processing remain unclear. In this study, we investigated neuromagnetic activities during a language task in a group of 28 monozygotic (MZ) and 12 dizygotic (DZ) adult twin pairs. We examined the spatio-temporal distribution of the event-related desynchronizations (ERDs) in the low gamma band (25–50Hz) using beamformer analyses and time–frequency analyses. Heritability was evaluated by comparing the respective MZ and DZ correlations. The genetic and environmental contributions were then estimated by structural equation modeling (SEM). We found that the peaks of the low gamma ERDs were localized to the left frontal area. The power of low gamma ERDs in this area exhibited higher similarity between MZ twins than that between DZ twins. SEM estimated the genetic contribution as approximately 50%. In addition, these powers were negatively correlated with the behavioral verbal scores. These results improve our understanding of how genetic and environmental factors influence cerebral activities during linguistic processes. |
Year | DOI | Venue |
|---|---|---|
2016 | 10.1016/j.neuroimage.2016.05.066 | NeuroImage |
Keywords | Field | DocType |
AIC,BA,CNTNAP2,DZ,ERD,ERSP,ERS,fMRI,ICC,MEG,MZ,MNI,SEM,SPM8,WMS-R | Heritability,Developmental psychology,Structural equation modeling,Candidate gene,Psychology,Gene–environment interaction,Genetic association,Gamma Rhythm,Twin study,Magnetoencephalography | Journal |
Volume | ISSN | Citations |
142 | 1053-8119 | 0 |
PageRank | References | Authors |
0.34 | 0 | 11 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Toshihiko Araki | 1 | 0 | 0.34 |
| Masayuki Hirata | 2 | 54 | 13.79 |
| Takufumi Yanagisawa | 3 | 21 | 6.27 |
| Hisato Sugata | 4 | 0 | 1.01 |
| Mai Onishi | 5 | 0 | 0.34 |
| Yoshiyuki Watanabe | 6 | 2 | 1.07 |
| Soshiro Ogata | 7 | 1 | 0.70 |
| Chika Honda | 8 | 0 | 0.34 |
| Kazuo Hayakawa | 9 | 0 | 0.34 |
| Shiro Yorifuji | 10 | 20 | 3.58 |
| Osaka Twin Research Group | 11 | 0 | 0.34 |