Name
Title | ||
|---|---|---|
3D: diversity, dynamics, differential testing - a proposed pipeline for analysis of next-generation sequencing T cell repertoire data. |
Abstract | ||
|---|---|---|
Our paper provides guidance to study the diversity and dynamics of NGS-based TCR repertoire profiling in a clinical context to ensure consistency and reproducibility of post-analysis. This analysis pipeline will provide an initial workflow for TCR sequencing data with serial time points and for comparing T cells in multiple compartments for a clinical study. |
Year | DOI | Venue |
|---|---|---|
2017 | 10.1186/s12859-017-1544-9 | BMC Bioinformatics |
Keywords | Field | DocType |
Binary similarity measure,Caner immunotherapy,Clonality,Differential testing,Diversity index,Dynamics index,Fold change,Next generation sequencing,T cell receptor,T cell repertoire | T-cell receptor,Cancer immunotherapy,Biology,Antigen,Repertoire,Acquired immune system,Bioinformatics,Genetics,Fold change,T cell,DNA microarray | Journal |
Volume | Issue | ISSN |
18 | 1 | 1471-2105 |
Citations | PageRank | References |
0 | 0.34 | 7 |
Authors | ||
6 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Li Zhang | 1 | 7 | 0.97 |
| Jason Cham | 2 | 0 | 0.34 |
| Alan Paciorek | 3 | 0 | 0.34 |
| James Trager | 4 | 0 | 0.34 |
| Nadeem Sheikh | 5 | 0 | 0.34 |
| Lawrence Fong | 6 | 0 | 0.34 |