Abstract | ||
---|---|---|
The models and methods we investigated in this manuscript is applicable and extendable to sequencing experiments where some biological replicates are available and the environmental variation is properly controlled. The CP-fit approach for assessing heritability was implemented for the first time to our knowledge. All the methods presented, as well as the generation of simulated sequencing data under either negative binomial or compound Poisson mixed models, are provided in the R package HeritSeq. |
Year | DOI | Venue |
---|---|---|
2017 | 10.1186/s12859-017-1539-6 | BMC Bioinformatics |
Keywords | Field | DocType |
Compound Poisson mixed model,Heritability,Negative binomial mixed model,RNAseq,Recombinant inbred panel,Variance partition coefficient | Heritability,Quantitative trait locus,Biology,Linear model,Trait,Mixed model,Negative binomial distribution,Poisson distribution,Bioinformatics,Expression quantitative trait loci,Genetics | Journal |
Volume | Issue | ISSN |
18 | 1 | 1471-2105 |
Citations | PageRank | References |
0 | 0.34 | 7 |
Authors | ||
9 |
Name | Order | Citations | PageRank |
---|---|---|---|
Pratyaydipta Rudra | 1 | 1 | 0.69 |
W. Jenny Shi | 2 | 0 | 0.34 |
Brian Vestal | 3 | 1 | 0.69 |
Pamela Russell | 4 | 11 | 1.37 |
Aaron Odell | 5 | 0 | 0.68 |
Robin D. Dowell | 6 | 354 | 86.17 |
Richard Radcliffe | 7 | 0 | 0.68 |
Laura M. Saba | 8 | 1 | 1.03 |
Katerina Kechris | 9 | 32 | 3.27 |