Title
Structured regularization for conditional Gaussian graphical models.
Abstract
Conditional Gaussian graphical models are a reparametrization of the multivariate linear regression model which explicitly exhibits (i) the partial covariances between the predictors and the responses, and (ii) the partial covariances between the responses themselves. Such models are particularly suitable for interpretability since partial covariances describe direct relationships between variables. In this framework, we propose a regularization scheme to enhance the learning strategy of the model by driving the selection of the relevant input features by prior structural information. It comes with an efficient alternating optimization procedure which is guaranteed to converge to the global minimum. On top of showing competitive performance on artificial and real datasets, our method demonstrates capabilities for fine interpretation, as illustrated on three high-dimensional datasets from spectroscopy, genetics, and genomics.
Year
DOI
Venue
2017
10.1007/s11222-016-9654-1
Statistics and Computing
Keywords
Field
DocType
Multivariate regression,Regularization,Sparsity,Conditional Gaussian graphical model,Structured elastic net,Regulatory motif,QTL study,Spectroscopy
Interpretability,Multivariate statistics,Bayesian multivariate linear regression,Regularization (mathematics),Gaussian,Artificial intelligence,Graphical model,Statistics,Machine learning,Mathematics
Journal
Volume
Issue
ISSN
27
3
0960-3174
Citations 
PageRank 
References 
1
0.40
10
Authors
3
Name
Order
Citations
PageRank
Julien Chiquet1285.01
Tristan Mary-Huard2818.45
Stéphane Robin314615.73