Title
Cancerous Nuclei Detection and Scoring in Breast Cancer Histopathological Images.
Abstract
Early detection and prognosis of breast cancer are feasible by utilizing histopathological grading of biopsy specimens. This research is focused on detection and grading of nuclear pleomorphism in histopathological images of breast cancer. The proposed method consists of three internal steps. First, unmixing colors of Hu0026E is used in the preprocessing step. Second, nuclei boundaries are extracted incorporating the center of cancerous nuclei which are detected by applying morphological operations and Difference of Gaussian filter on the preprocessed image. Finally, segmented nuclei are scored to accomplish one parameter of the Nottingham grading system for breast cancer. In this approach, the nuclei area, chromatin density, contour regularity, and nucleoli presence, are features for nuclear pleomorphism scoring. Experimental results showed that the proposed algorithm, with an accuracy of 86.6%, made significant advancement in detecting cancerous nuclei compared to existing methods in the related literature.
Year
Venue
Field
2016
arXiv: Computer Vision and Pattern Recognition
Early detection,Breast cancer,Pattern recognition,Computer science,Biopsy,Preprocessor,Artificial intelligence,Pleomorphism (cytology),Difference of Gaussians
DocType
Volume
Citations 
Journal
abs/1612.01237
0
PageRank 
References 
Authors
0.34
0
4
Name
Order
Citations
PageRank
Pegah Faridi100.68
Habibollah Danyali24911.07
Mohammad Sadegh Helfroush37011.30
Mojgan Akbarzadeh Jahromi400.34