Title
High Sensitivity Detection of CdSe/ZnS Quantum Dot-Labeled DNA Based on N-type Porous Silicon Microcavities.
Abstract
N-type macroporous silicon microcavity structures were prepared using electrochemical etching in an HF solution in the absence of light and oxidants. The CdSe/ZnS water-soluble quantum dot-labeled DNA target molecules were detected by monitoring the microcavity reflectance spectrum, which was characterized by the reflectance spectrum defect state position shift resulting from changes to the structures' refractive index. Quantum dots with a high refractive index and DNA coupling can improve the detection sensitivity by amplifying the optical response signals of the target DNA. The experimental results show that DNA combined with a quantum dot can improve the sensitivity of DNA detection by more than five times.
Year
DOI
Venue
2017
10.3390/s17010080
SENSORS
Keywords
Field
DocType
N-type porous silicon,quantum dot labeling,QD-DNA,reflectance spectrum
Quantum,Analytical chemistry,Porous silicon,Molecule,DNA,Engineering,High-refractive-index polymer,Optoelectronics,Quantum dot,Silicon,Refractive index
Journal
Volume
Issue
ISSN
17
1.0
1424-8220
Citations 
PageRank 
References 
1
0.43
0
Authors
5
Name
Order
Citations
PageRank
Changwu Lv110.43
Zhenhong Jia22915.13
Jie Lv341.76
Hongyan Zhang453.74
Yanyu Li510.43