Name
Title | ||
|---|---|---|
Automated Detector Of High Frequency Oscillations In Epilepsy Based On Maximum Distributed Peak Points |
Abstract | ||
|---|---|---|
High frequency oscillations (HFOs) are considered as biomarker for epileptogenicity. Reliable automation of HFOs detection is necessary for rapid and objective analysis, and is determined by accurate computation of the baseline. Although most existing automated detectors measure baseline accurately in channels with rare HFOs, they lose accuracy in channels with frequent HFOs. Here, we proposed a novel algorithm using the maximum distributed peak points method to improve baseline determination accuracy in channels with wide HFOs activity ranges and calculate a dynamic baseline. Interictal ripples (80-200 Hz), fast ripples (FRs, 200-500 Hz) and baselines in intracerebral EEGs from seven patients with intractable epilepsy were identified by experienced reviewers and by our computer-automated program, and the results were compared. We also compared the performance of our detector to four well-known detectors integrated in RIPPLELAB. The sensitivity and specificity of our detector were, respectively, 71% and 75% for ripples and 66% and 84% for FRs. Spearman's rank correlation coefficient comparing automated and manual detection was 0.896 +/- 0.080 for ripples and 0.974 +/- 0.030 for FRs (p < 0.01). In comparison to other detectors, our detector had a relatively higher sensitivity and specificity. In conclusion, our automated detector is able to accurately calculate a dynamic iEEG baseline in different HFO activity channels using the maximum distributed peak points method, resulting in higher sensitivity and specificity than other available HFO detectors. |
Year | DOI | Venue |
|---|---|---|
2018 | 10.1142/S0129065717500290 | INTERNATIONAL JOURNAL OF NEURAL SYSTEMS |
Keywords | Field | DocType |
High frequency oscillations, automated detector, maximum distributed peak points, epilepsy, dynamic baseline | Oscillation,Pattern recognition,Computer science,Automation,Epilepsy,Artificial intelligence,Detector,Ictal,Computation | Journal |
Volume | Issue | ISSN |
28 | 1 | 0129-0657 |
Citations | PageRank | References |
1 | 0.41 | 7 |
Authors | ||
11 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Guo-Ping Ren | 1 | 1 | 0.41 |
| Jiaqing Yan | 2 | 6 | 2.51 |
| Zhi-Xin Yu | 3 | 1 | 0.41 |
| Dan Wang | 4 | 101 | 40.29 |
| Xiaonan Li | 5 | 163 | 12.91 |
| Shan-Shan Mei | 6 | 1 | 0.74 |
| Jin-Dong Dai | 7 | 1 | 0.41 |
| Xiaoli Li | 8 | 490 | 57.90 |
| Yun-Lin Li | 9 | 1 | 0.41 |
| Xiao-Fei Wang | 10 | 1 | 0.41 |
| Xiao-Feng Yang | 11 | 1 | 0.41 |