Abstract | ||
---|---|---|
The fuzzy oil drop model was applied to characterize the hydrophobic core structure in plant carboxylesterase. The characteristics revealed the status of beta-sheets in the central part of the molecule as discordant as opposed to the expected hydrophobicity distribution. Particularly, the beta-strands and helices in close proximity to the enzymatic residues recognized as discordant with respect to the ideal hydrophobicity distribution of hydrophobic core are of high importance. It is assumed that this local irregularity is the form of coding the specificity of enzymes. The protein under consideration appears to be the next example proving this assumption. |
Year | DOI | Venue |
---|---|---|
2017 | 10.1515/bams-2017-0001 | BIO-ALGORITHMS AND MED-SYSTEMS |
Keywords | Field | DocType |
carboxylesterase,fuzzy oil drop model,hydrolase,hydrophobicity | Carboxylesterase,Biochemistry,Chemistry,Hydrolase | Journal |
Volume | Issue | ISSN |
13 | 1 | 1895-9091 |
Citations | PageRank | References |
0 | 0.34 | 2 |
Authors | ||
4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Mateusz Banach | 1 | 7 | 8.88 |
Leszek Konieczny | 2 | 67 | 22.55 |
Zdzisław Wiśniowski | 3 | 3 | 3.16 |
Irena Roterman | 4 | 78 | 30.08 |