Paper Info
Title
Deep-Brain Transcranial Stimulation: A Novel Approach For High 3-D Resolution
Abstract
This research was performed to investigate the ability of transcranial magnetic stimulation (TMS) to evoke the deeper areas of the brain with a minimal impact on non-target areas. To reach this goal, a novel core design in a semi-hexagonal shape with the arrow tips was utilized to collect a magnetic field in the selected target region. In addition, a new circuit topology was presented to generate stimulative pulses with optimal amplitude, frequency, and duration. For the first time in this research voxel resolution was proposed and exploited to evaluate the TMS system accuracy. To study the induced potential in different parts of the brain and its related resolution, a custom-made recording electrode and a micromanipulator were employed. They provided the linear movement in all Rostral/Caudal, Dorsal/Ventral, and Medial/Lateral orientations. The ARM cortex-M microcontroller managed the stimulation and recording sessions. After performing the finite element analysis, the researcher developed a prototype of the proposed system and tested it in vivo on the intact WAG/Raj rat. The results showed that spatial resolution could be significantly enhanced by employing the proposed TMS concept. The outcome of animal trials have raised some hopes to apply the knowledge of this article in the clinical contexts.
Year
Venue
Keywords
2017
IEEE ACCESS
Transcranial magnetic stimulation, target selectivity, stimulation coil/core shape, measuring voxel resolution
Field
DocType
Volume
Voxel,Biomedical engineering,Linear motion,Transcranial magnetic stimulation,Computer science,Microcontroller,Image resolution,Micromanipulator,Stimulation,Topology (electrical circuits),Distributed computing
Journal
5
ISSN
Citations 
PageRank 
2169-3536
0
0.34
References 
Authors
3
4
Name
Order
Citations
PageRank
Majid Memarian Sorkhabi100.34
Javad Frounchi2244.78
Parviz Shahabi301.35
Hadi Veladi400.34