Title
Vascular segmentation of head phase-contrast magnetic resonance angiograms using grayscale and shape features.
Abstract
A novel method is proposed to extract 3D vascular structures from head phase-contrast magnetic resonance angiography dataset.It combines vascular grayscale and shape features based on DempsterShafer evidence theory.A cost function is modeled to differentially punish the mis-segmentation of the background and blood vessels.The segmentation ratio coefficient is proposed to prevent over-segmentation. Background and objectiveIn neurosurgery planning, vascular structures must be predetermined, which can guarantee the security of the operation carried out in the case of avoiding blood vessels. In this paper, an automatic algorithm of vascular segmentation, which combined the grayscale and shape features of the blood vessels, is proposed to extract 3D vascular structures from head phase-contrast magnetic resonance angiography dataset. MethodsFirst, a cost function of mis-segmentation is introduced on the basis of traditional Bayesian statistical classification, and the blood vessel of weak grayscale that tended to be misclassified into background will be preserved. Second, enhanced vesselness image is obtained according to the shape-based multiscale vascular enhancement filter. Third, a new reconstructed vascular image is established according to the fusion of vascular grayscale and shape features using DempsterShafer evidence theory; subsequently, the corresponding segmentation structures are obtained. Finally, according to the noise distribution characteristic of the data, segmentation ratio coefficient, which increased linearly from top to bottom, is proposed to control the segmentation result, thereby preventing over-segmentation. ResultsExperiment results show that, through the proposed method, vascular structures can be detected not only when both grayscale and shape features are strong, but also when either of them is strong. Compared with traditional grayscale feature- and shape feature-based methods, it is better in the evaluation of testing in segmentation accuracy, and over-segmentation and under-segmentation ratios. ConclusionsThe proposed grayscale and shape features combined vascular segmentation is not only effective but also accurate. It may be used for diagnosis of vascular diseases and planning of neurosurgery.
Year
DOI
Venue
2017
10.1016/j.cmpb.2017.02.008
Computer Methods and Programs in Biomedicine
Keywords
Field
DocType
Bayesian classification,Dempster–Shafer evidence theory,Multiscale vascular enhancement,Neurosurgery,Vascular segmentation
Phase contrast microscopy,Computer vision,Scale-space segmentation,Naive Bayes classifier,Segmentation,Computer science,Artificial intelligence,Magnetic resonance angiography,Statistical classification,Grayscale,Magnetic resonance imaging
Journal
Volume
Issue
ISSN
142
C
0169-2607
Citations 
PageRank 
References 
2
0.40
21
Authors
6
Name
Order
Citations
PageRank
Ruoxiu Xiao1275.94
Hui Ding290233.37
Fangwen Zhai321.07
Tong Zhao4147.30
Wenjing Zhou591.89
Wang Guangzhi6269.72