Title
A Semantic Cross-Species Derived Data Management Application.
Abstract
Managing dynamic information in large multi-site, multi-species, and multi-discipline consortia is a challenging task for data management applications. Often in academic research studies the goals for informatics teams are to build applications that provide extract-transform-load (ETL) functionality to archive and catalog source data that has been collected by the research teams. In consortia that cross species and methodological or scientific domains, building interfaces which supply data in a usable fashion and make intuitive sense to scientists from dramatically different backgrounds increases the complexity for developers. Further, reusing source data from outside one’s scientific domain is fraught with ambiguities in understanding the data types, analysis methodologies, and how to combine the data with those from other research teams. We report on the design, implementation, and performance of a semantic data management application to support the NIMH funded Conte Center at the University of California, Irvine. The Center is testing a theory of the consequences of “fragmented” (unpredictable, high entropy) early-life experiences on adolescent cognitive and emotional outcomes in both humans and rodents. It employs cross-species neuroimaging, epigenomic, molecular, and neuroanatomical approaches in humans and rodents to assess the potential consequences of fragmented unpredictable experience on brain structure and circuitry. To address this multi-technology, multi-species approach, the system uses semantic web techniques based on the Neuroimaging Data Model (NIDM) to facilitate data ETL functionality. We find this approach enables a low-cost, easy to maintain, and semantically meaningful information management system, enabling the diverse research teams to access and use the data.
Year
DOI
Venue
2017
10.5334/dsj-2017-045
Data Science Journal
Field
DocType
Volume
USable,Data science,Management information systems,Data mining,Source data,Computer science,Semantic Web,Data type,Informatics,World Wide Web,Data model,Data management,Database
Journal
abs/1706.07835
Citations 
PageRank 
References 
0
0.34
8
Authors
7
Name
Order
Citations
PageRank
David B. Keator122820.24
Jinran Chen200.34
B. Nolan Nichols300.34
Fariba Fana4112.27
Hal Stern580.88
Tallie Z. Baram600.68
Steven L. Small715822.15