Title
Influenza Research Database: An Integrated Bioinformatics Resource For Influenza Virus Research
Abstract
The Influenza Research Database (IRD) is a U.S. National Institute of Allergy and Infectious Diseases (NIAID)-sponsored Bioinformatics Resource Center dedicated to providing bioinformatics support for influenza virus research. IRD facilitates the research and development of vaccines, diagnostics and therapeutics against influenza virus by providing a comprehensive collection of influenza-related data integrated from various sources, a growing suite of analysis and visualization tools for data mining and hypothesis generation, personal workbench spaces for data storage and sharing, and active user community support. Here, we describe the recent improvements in IRD including the use of cloud and high performance computing resources, analysis and visualization of user-provided sequence data with associated metadata, predictions of novel variant proteins, annotations of phenotype-associated sequence markers and their predicted phenotypic effects, hemagglutinin (HA) clade classifications, an automated tool for HA subtype numbering conversion, linkouts to disease event data and the addition of host factor and antiviral drug components. All data and tools are freely available without restriction from the IRD website at https://www.fludb.org.
Year
DOI
Venue
2017
10.1093/nar/gkw857
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Orthomyxoviridae,Virus,Host factor,Biology,Influenza research,Bioinformatics,Virology
Journal
45
Issue
ISSN
Citations 
D1
0305-1048
1
PageRank 
References 
Authors
0.43
4
28