Title
DrugCentral: online drug compendium.
Abstract
DrugCentral (http://drugcentral.org) is an open-access online drug compendium. DrugCentral integrates structure, bioactivity, regulatory, pharmacologic actions and indications for active pharmaceutical ingredients approved by FDA and other regulatory agencies. Monitoring of regulatory agencies for new drugs approvals ensures the resource is up-to- date. DrugCentral integrates content for active ingredients with pharmaceutical formulations, indexing drugs and drug label annotations, complementing similar resources available online. Its complementarity with other online resources is facilitated by cross referencing to external resources. At the molecular level, DrugCentral bridges drug-target interactions with pharmacological action and indications. The integration with FDA drug labels enables text mining applications for drug adverse events and clinical trial information. Chemical structure overlap between DrugCentral and five online drug resources, and the overlap between DrugCentral FDA-approved drugs and their presence in four different chemical collections, are discussed. DrugCentral can be accessed via the web application or downloaded in relational database format.
Year
DOI
Venue
2017
10.1093/nar/gkw993
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Active ingredient,World Wide Web,Compendium,Pharmacologic action,Biology,Relational database,Genetics,Drug,Drug compounding,Drug labeling,The Internet
Journal
45
Issue
ISSN
Citations 
D1
0305-1048
16
PageRank 
References 
Authors
0.77
15
8
Name
Order
Citations
PageRank
Oleg Ursu1394.57
Jayme Holmes2282.91
Jeffrey Knockel37010.49
Cristian Bologa4293.54
Jeremy J. Yang5434.62
Stephen L. Mathias6364.80
Stuart J. Nelson730640.05
Tudor I Oprea835946.89