Abstract | ||
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The human immunodeficiency virus (HIV) is associated with one of the most widespread infectious disease, the acquired immunodeficiency syndrome ( AIDS). The development of antiretroviral drugs and methods for virus detection requires a comprehensive analysis of the HIV genomic diversity, particularly in the binding sites of oligonucleotides. Here, we describe a versatile online database (HIVoligoDB) with oligonucleotides selected for the diagnosis of HIV and treatment of AIDS. Currently, the database provides an interface for visualization, analysis and download of 380 HIV-1 and 65 HIV-2 oligonucleotides annotated according to curated reference genomes. The database also allows the selection of the most conserved HIV genomic regions for the development of molecular diagnostic assays and sequence-based candidate therapeutics. |
Year | DOI | Venue |
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2017 | 10.1093/database/bax005 | DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION |
Field | DocType | Volume |
Data mining,Information retrieval,Computer science | Journal | 2017 |
Issue | ISSN | Citations |
1 | 1758-0463 | 0 |
PageRank | References | Authors |
0.34 | 0 | 3 |
Name | Order | Citations | PageRank |
---|---|---|---|
João Carneiro | 1 | 26 | 12.30 |
Adriana Resende | 2 | 0 | 0.34 |
Filipe Pereira | 3 | 1 | 1.06 |