Paper Info
Title
The Preventive Control of Zoonotic Visceral Leishmaniasis: Efficacy and Economic Evaluation.
Abstract
Zoonotic Visceral Leishmaniasis (ZVL) is one of the world's deadliest and neglected infectious diseases, according to World Health Organization. This disease is one of major human and veterinary medical significance. The sandfly and the reservoir in urban areas remain among the major challenges for the control activities. In this paper, we evaluated five control strategies (positive dog elimination, insecticide impregnated dog collar, dog vaccination, dog treatment, and sandfly population control), considering disease control results and cost-effectiveness. We elaborated a mathematical model based on a set of differential equations in which three populations were represented (human, dog, and sandfly). Humans and dogs were divided into susceptible, latent, clinically ill, and recovery categories. Sandflies were divided into noninfected, infected, and infective. As the main conclusions, the insecticide impregnated dog collar was the strategy that presented the best combination between disease control and cost-effectiveness. But, depending on the population target, the control results and cost-effectiveness of each strategy may differ. More and detailed studies are needed, specially one which optimizes the control considering more than one strategy in activity.
Year
DOI
Venue
2017
10.1155/2017/4797051
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE
Field
DocType
Volume
Population,Vaccination,Environmental health,Artificial intelligence,Medicine,Disease,Sandfly,Preventive control,Economic evaluation,Population control,Visceral leishmaniasis,Machine learning,Veterinary medicine
Journal
2017
ISSN
Citations 
PageRank 
1748-670X
1
0.36
References 
Authors
0
3
Name
Order
Citations
PageRank
Helio Junji Shimozako110.36
Jianhong Wu245877.19
Eduardo Massad33312.99