Title
Post-Marketing Drug Safety Evaluation Using Data Mining Based On Faers
Abstract
Healthcare is going through a big data revolution. The amount of data generated by healthcare is expected to increase significantly in the coming years. Therefore, efficient and effective data processing methods are required to transform data into information. In addition, applying statistical analysis can transform the information into useful knowledge. We developed a data mining method that can uncover new knowledge in this enormous field for clinical decision making while generating scientific methods and hypotheses. The proposed pipeline can be generally applied to a variety of data mining tasks in medical informatics. For this study, we applied the proposed pipeline for post-marketing surveillance on drug safety using FAERS, the data warehouse created by FDA. We used 14 kinds of neurology drugs to illustrate our methods. Our result indicated that this approach can successfully reveal insight for further drug safety evaluation.
Year
DOI
Venue
2017
10.1007/978-3-319-61845-6_38
DATA MINING AND BIG DATA, DMBD 2017
Keywords
Field
DocType
Data mining, Post-marketing surveillance, Zero-truncated negative binomial regression model
Data science,Data warehouse,Data mining,Data processing,Clinical decision making,Computer science,Health informatics,Big data,Postmarketing surveillance,Statistical analysis,Scientific method
Conference
Volume
ISSN
Citations 
10387
0302-9743
0
PageRank 
References 
Authors
0.34
2
6
Name
Order
Citations
PageRank
Rui Duan144.90
Xinyuan Zhang213.74
Jingcheng Du33016.40
Jing Huang401.35
Cui Tao511822.10
Yong Chen600.68