Title
Primal-mixed formulations for reaction-diffusion systems on deforming domains
Abstract
We propose a finite element formulation for a coupled elasticity-reaction-diffusion system written in a fully Lagrangian form and governing the spatio-temporal interaction of species inside an elastic, or hyper-elastic body. A primal weak formulation is the baseline model for the reaction-diffusion system written in the deformed domain, and a finite element method with piecewise linear approximations is employed for its spatial discretization. On the other hand, the strain is introduced as mixed variable in the equations of elastodynamics, which in turn acts as coupling field needed to update the diffusion tensor of the modified reaction-diffusion system written in a deformed domain. The discrete mechanical problem yields a mixed finite element scheme based on row-wise Raviart-Thomas elements for stresses, Brezzi-Douglas-Marini elements for displacements, and piecewise constant pressure approximations. The application of the present framework in the study of several coupled biological systems on deforming geometries in two and three spatial dimensions is discussed, and some illustrative examples are provided and extensively analyzed.
Year
DOI
Venue
2015
10.1016/j.jcp.2015.07.018
Journal of Computational Physics
Keywords
Field
DocType
Mixed finite elements,Reaction–diffusion systems,Excitable media,Moving domains,Linear and nonlinear elasticity,Single cell mechanics,Active strain
Discretization,Mathematical optimization,Coupling,Mathematical analysis,Finite element method,Reaction–diffusion system,Elasticity (economics),Piecewise,Weak formulation,Mathematics,Mixed finite element method
Journal
Volume
Issue
ISSN
299
C
0021-9991
Citations 
PageRank 
References 
1
0.42
12
Authors
1
Name
Order
Citations
PageRank
Ricardo Ruiz-Baier17713.60