Title
Automatic Classification of Tremor Severity in Parkinson's Disease Using a Wearable Device.
Abstract
Although there is clinical demand for new technology that can accurately measure Parkinsonian tremors, automatic scoring of Parkinsonian tremors using machine-learning approaches has not yet been employed. This study aims to fill this gap by proposing machine-learning algorithms as a way to predict the Unified Parkinson's Disease Rating Scale (UPDRS), which are similar to how neurologists rate scores in actual clinical practice. In this study, the tremor signals of 85 patients with Parkinson's disease (PD) were measured using a wrist-watch-type wearable device consisting of an accelerometer and a gyroscope. The displacement and angle signals were calculated from the measured acceleration and angular velocity, and the acceleration, angular velocity, displacement, and angle signals were used for analysis. Nineteen features were extracted from each signal, and the pairwise correlation strategy was used to reduce the number of feature dimensions. With the selected features, a decision tree (DT), support vector machine (SVM), discriminant analysis (DA), random forest (RF), and k-nearest-neighbor (kNN) algorithm were explored for automatic scoring of the Parkinsonian tremor severity. The performance of the employed classifiers was analyzed using accuracy, recall, and precision, and compared to other findings in similar studies. Finally, the limitations and plans for further study are discussed.
Year
DOI
Venue
2017
10.3390/s17092067
SENSORS
Keywords
Field
DocType
tremor,UPDRS,automatic scoring,Parkinson's disease,wearable device,machine learning algorithm
Decision tree,Gyroscope,Angular velocity,Accelerometer,Support vector machine,Speech recognition,Acceleration,Linear discriminant analysis,Engineering,Random forest
Journal
Volume
Issue
ISSN
17
9.0
1424-8220
Citations 
PageRank 
References 
8
0.83
12
Authors
8
Name
Order
Citations
PageRank
Hyo Seon Jeon1172.42
Lee, W.K.291.22
Hyeyoung Park319432.70
Hong Ji Lee4325.03
Sang Kyong Kim5101.53
Han Byul Kim681.17
Beom S. Jeon7211.76
Kwang Suk Park826646.43