Title
Relationship Between Heart Rate Excursion And Apnea Duration In Patients With Obstructive Sleep Apnea
Abstract
Obstructive Sleep Apnea (OSA) is a sleep disorder with a high prevalence in the general population. It is a risk factor for many cardiovascular diseases, and an independent risk factor for cerebrovascular diseases such as stroke. After an apnea episode, both arterial blood pressure and cerebral bood flow velocity change in function of the apnea duration (AD). We hypothesized that the relative excursion in heart rate (Delta HR), defined as the percentage difference between the maximum and the minimum heart rate values associated to an obstructive apnea event, is also related to AD. In this work we studied the relationship between apnea-related Delta HR and AD in a population of eight patients with severe OSA. Delta HR and AD showed a moderate but statistically significant correlation (p < 0.0001) in a total of 1454 obstructive apneas analyzed. The average heart rate excursion for apneas with AD >= 30s (Delta HR = 31.29 +/- 6.64%) was significantly greater (p = 0.0002) than for apneas with AD is an element of [10; 20) s (<(Delta HR)over bar> = 18.14 +/- 3.08%). We also observed that patients with similar Apnea-Hypopnea Index (AHI) may exhibit remarkably different distributions of Delta HR and AD, and that patients with a high AHI need not have a higher average Delta HR than others with a lower severity index. We conclude that the overall apnea-induced heart rate excursion is partially explained by the duration of apnoeic episodes, and it may be a simple measure of the cardiovascular stress associated with OSA that is not directly reflected in the AHI.
Year
DOI
Venue
2017
10.1109/EMBC.2017.8037129
2017 39TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)
Field
DocType
Volume
Population,Obstructive sleep apnea,Minimum Heart Rate,Anesthesia,Apnea,Blood pressure,Sleep disorder,Heart rate,Medicine,Risk factor
Conference
2017
ISSN
Citations 
PageRank 
1094-687X
0
0.34
References 
Authors
1
4
Name
Order
Citations
PageRank
J Solà-Soler173.40
Beatriz F. Giraldo22814.06
José Antonio Fiz3153.55
R Jané413143.71