Title
Injection moulded microneedle sensor for real-time wireless pH monitoring
Abstract
This paper describes the development of an array of individually addressable pH sensitive microneedles using injection moulding and their integration within a portable device for real-time wireless recording of pH distributions in biological samples. The fabricated microneedles are subjected to gold patterning followed by electrodeposition of iridium oxide to sensitize them to 0.07 units of pH change. Miniaturised electronics suitable for the sensors readout, analog-to-digital conversion and wireless transmission of the potentiometric data are embodied within the device, enabling it to measure real-time pH of soft biological samples such as muscles. In this paper, real-time recording of the cardiac pH distribution, during ischemia followed by reperfusion cycles in cardiac muscles of male Wistar rats has been demonstrated by using the microneedle array.
Year
DOI
Venue
2017
10.1109/EMBC.2017.8036794
2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Keywords
Field
DocType
Animals,Electroplating,Hydrogen-Ion Concentration,Injections,Male,Needles,Potentiometry,Rats,Rats, Wistar,Time Factors,Wireless Technology
Biomedical engineering,Injection moulding,Wireless,Computer science,Electronic engineering,Electronics,Wireless transmission,Iridium oxide,Electroplating,Molding (process)
Conference
Volume
ISSN
ISBN
2017
1557-170X
978-1-5090-2810-8
Citations 
PageRank 
References 
0
0.34
0
Authors
6
Name
Order
Citations
PageRank
Khalid B. Mirza102.70
Claudio Zuliani200.34
Benjamin Hou3245.65
f s ng462.36
Nicholas S. Peters511810.60
Christofer Toumazou626559.06