Abstract | ||
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We demonstrate a diagnostics platform which integrates an ISFET array and a temperature control loop for isothermal DNA detection. The controller maintains a temperature of 63 degrees C to perform nucleic acid amplification which is detected by the on-chip sensors. The 32x32 ISFET array is first calibrated to cancel trapped charge and then measures the change in the pH of the reaction. The sensor data is sent to a microcontroller and the reaction is monitored in real-time using a MATLAB interface. Experiments confirm a change of 0.9 pH when tested for the presence of RNA associated with the Zika virus. |
Year | Venue | Field |
---|---|---|
2017 | 2017 IEEE INTERNATIONAL SYMPOSIUM ON CIRCUITS AND SYSTEMS (ISCAS) | ISFET,Zika virus,Control theory,System on a chip,Computer science,Temperature control,Electronic engineering,CMOS,Microcontroller,Temperature measurement |
DocType | ISSN | Citations |
Conference | 0271-4302 | 0 |
PageRank | References | Authors |
0.34 | 0 | 9 |
Name | Order | Citations | PageRank |
---|---|---|---|
Nicolas Moser | 1 | 1 | 5.78 |
Jesus Rodriguez-Manzano | 2 | 3 | 4.14 |
Ling-Shan Yu | 3 | 1 | 0.70 |
Melpomeni Kalofonou | 4 | 1 | 1.72 |
Sara de Mateo | 5 | 0 | 1.35 |
Xiaoxiang Li | 6 | 0 | 0.68 |
Tor Sverre Lande | 7 | 128 | 45.26 |
Christofer Toumazou | 8 | 265 | 59.06 |
Pantelis Georgiou | 9 | 111 | 50.64 |