Title
Machine Learning and Knowledge Extraction in Digital Pathology Needs an Integrative Approach
Abstract
During the last decade pathology has benefited from the rapid progress of image digitizing technologies, which led to the development of scanners, capable to produce so-called Whole Slide images (WSI) which can be explored by a pathologist on a computer screen comparable to the conventional microscope and can be used for diagnostics, research, archiving and also education and training. Digital pathology is not just the transformation of the classical microscopic analysis of histological slides by pathologists to just a digital visualization. It is a disruptive innovation that will dramatically change medical work-flows in the coming years and help to foster personalized medicine. Really powerful gets a pathologist if she/he is augmented by machine learning, e.g. by support vector machines, random forests and deep learning. The ultimate benefit of digital pathology is to enable to learn, to extract knowledge and to make predictions from a combination of heterogenous data, i.e. the histological image, the patient history and the *omics data. These challenges call for integrated/integrative machine learning approach fostering transparency, trust, acceptance and the ability to explain step-by-step why a decision has been made.
Year
DOI
Venue
2015
10.1007/978-3-319-69775-8_2
Lecture Notes in Artificial Intelligence
Keywords
Field
DocType
Digital pathology,Data integration,Integrative machine learning,Deep learning,Transfer learning
Data science,Data integration,Disruptive innovation,Computer science,Visualization,Transfer of learning,Digital pathology,Knowledge extraction,Artificial intelligence,Deep learning,Machine learning,Personalized medicine
Conference
Volume
ISSN
Citations 
10344
0302-9743
1
PageRank 
References 
Authors
0.36
0
7
Name
Order
Citations
PageRank
Andreas Holzinger12886253.75
Bernd Malle2223.17
Peter Kieseberg318729.39
Peter M. Roth497247.31
Heimo Müller535828.60
Robert Reihs6161.72
Kurt Zatloukal738229.67