Title
Real-Time Two-Dimensional Magnetic Particle Imaging for Electromagnetic Navigation in Targeted Drug Delivery.
Abstract
Magnetic nanoparticles (MNPs) are effective drug carriers. By using electromagnetic actuated systems, MNPs can be controlled noninvasively in a vascular network for targeted drug delivery (TDD). Although drugs can reach their target location through capturing schemes of MNPs by permanent magnets, drugs delivered to non-target regions can affect healthy tissues and cause undesirable side effects. Real-time monitoring of MNPs can improve the targeting efficiency of TDD systems. In this paper, a two-dimensional (2D) real-time monitoring scheme has been developed for an MNP guidance system. Resovist particles 45 to 65 nm in diameter (5 nm core) can be monitored in real-time (update rate = 2 Hz) in 2D. The proposed 2D monitoring system allows dynamic tracking of MNPs during TDD and renders magnetic particle imaging-based navigation more feasible.
Year
DOI
Venue
2017
10.3390/s17092050
SENSORS
Keywords
Field
DocType
magnetic particle imaging,navigation resolution,magnetic nanoparticles
Magnetic particle imaging,Biomedical engineering,Nanotechnology,Monitoring system,Magnet,Drug carrier,Targeted drug delivery,Magnetic nanoparticles,Engineering
Journal
Volume
Issue
ISSN
17
9.0
1424-8220
Citations 
PageRank 
References 
0
0.34
7
Authors
4
Name
Order
Citations
PageRank
Tuan-Anh Le111.06
Xingming Zhang200.68
Ali Kafash Hoshiar321.76
Jungwon Yoon453.37