Title | ||
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Real-Time Two-Dimensional Magnetic Particle Imaging for Electromagnetic Navigation in Targeted Drug Delivery. |
Abstract | ||
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Magnetic nanoparticles (MNPs) are effective drug carriers. By using electromagnetic actuated systems, MNPs can be controlled noninvasively in a vascular network for targeted drug delivery (TDD). Although drugs can reach their target location through capturing schemes of MNPs by permanent magnets, drugs delivered to non-target regions can affect healthy tissues and cause undesirable side effects. Real-time monitoring of MNPs can improve the targeting efficiency of TDD systems. In this paper, a two-dimensional (2D) real-time monitoring scheme has been developed for an MNP guidance system. Resovist particles 45 to 65 nm in diameter (5 nm core) can be monitored in real-time (update rate = 2 Hz) in 2D. The proposed 2D monitoring system allows dynamic tracking of MNPs during TDD and renders magnetic particle imaging-based navigation more feasible. |
Year | DOI | Venue |
---|---|---|
2017 | 10.3390/s17092050 | SENSORS |
Keywords | Field | DocType |
magnetic particle imaging,navigation resolution,magnetic nanoparticles | Magnetic particle imaging,Biomedical engineering,Nanotechnology,Monitoring system,Magnet,Drug carrier,Targeted drug delivery,Magnetic nanoparticles,Engineering | Journal |
Volume | Issue | ISSN |
17 | 9.0 | 1424-8220 |
Citations | PageRank | References |
0 | 0.34 | 7 |
Authors | ||
4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Tuan-Anh Le | 1 | 1 | 1.06 |
Xingming Zhang | 2 | 0 | 0.68 |
Ali Kafash Hoshiar | 3 | 2 | 1.76 |
Jungwon Yoon | 4 | 5 | 3.37 |