Name
Title | ||
|---|---|---|
Altered adenosine 2A and dopamine D2 receptor availability in the 6-hydroxydopamine-treated rats with and without levodopa-induced dyskinesia. |
Abstract | ||
|---|---|---|
Several lines of evidence imply alterations in adenosine signaling in Parkinson's disease (PD). Here, we investigated cerebral changes in adenosine 2A receptor (A2AR) availability in 6-hydroxydopamine (6-OHDA)-lesioned rats with and without levodopa-induced dyskinesia (LID) using positron-emission tomography (PET) with [11C]preladenant. In parallel dopamine type 2 receptor (D2R) imaging with [11C]raclopride PET and behavioral tests for motor and cognitive function were performed. |
Year | DOI | Venue |
|---|---|---|
2017 | 10.1016/j.neuroimage.2017.05.066 | NeuroImage |
Keywords | Field | DocType |
A2AR,AIM,ANOVA,BPND,CNS,D2R,L-DOPA,LID,MRTM,6-OHDA,PD,PET,SNpc,SPM,SRTM,SD,VOI | Hydroxydopamine,Preladenant,Internal medicine,Striatum,Raclopride,Psychology,Levodopa-induced dyskinesia,Dopamine,Abnormal involuntary movement,Endocrinology,Basal ganglia | Journal |
Volume | Issue | ISSN |
157 | SUPnan | 1053-8119 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
6 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Xiaoyun Zhou | 1 | 0 | 0.34 |
| Janine Doorduin | 2 | 0 | 0.68 |
| Philip H Elsinga | 3 | 0 | 0.68 |
| Rudi A Dierckx | 4 | 0 | 0.68 |
| Erik F. J. de Vries | 5 | 1 | 0.69 |
| Cindy Casteels | 6 | 6 | 1.86 |