Title
Synthesis aware sample preparation techniques using random sample sets in DMFB
Abstract
Digital Microfluidic Biochips in recent years have emerged as a major feasible alternative platform for droplet based microfluidic operations within a miniaturized substrate. These devices find applications in the areas involving medical diagnostics, biochemical analysis and environmental toxicity monitoring issues. Formation of the sequencing graph for sample preparation followed by architecture level synthesis is the initial primary procedure for design automation of DMFBs. In this paper we proposed a technique for sample preparation using base solutions for a given random set of samples. The technique is developed to be synthesis aware in order to enable efficient use of resources in terms of modules for pipelined synthesis. The advantages of the proposed method is i) optimal resource utilization in terms of number of modules and samples and ii) efficient enhancement in overall execution time for the bioassay. The simulation is carried out with a given set of random samples as well as with a specified set of samples with Gaussian distribution. The results show encouraging improvements in i) number of sample utilizations, ii)number of mix-split operations iii)the formation of the number of waste droplets and iv) the actual number of modules used for execution of the overall bioassay.
Year
DOI
Venue
2016
10.1109/ISVDAT.2016.8064872
2016 20th International Symposium on VLSI Design and Test (VDAT)
Keywords
Field
DocType
sample preparation,random sample sets,synthesis,pipelining,dilution,modules,resource utilization,bioassay,overall execution time,algorithms
Resource management,Algorithm design,Biochip,Computer science,Sample preparation,Electronic engineering,Gaussian,Electronic design automation,Minification,Sampling (statistics),Embedded system
Conference
ISSN
ISBN
Citations 
2475-8620
978-1-5090-1423-1
0
PageRank 
References 
Authors
0.34
10
3
Name
Order
Citations
PageRank
Pranab Roy14714.15
Sudeshna Chakraborty200.34
Hafizur Rahaman336891.37