Title
Automatic 3D Single Neuron Reconstruction with Exhaustive Tracing
Abstract
The digital reconstruction of neuronal morphology from single neurons, also called neuron tracing, is a crucial process to gain a better understanding of the relationship and connections in neuronal networks. However, the fully automation of neuron tracing remains a big challenge due to the biological diversity of the neuronal morphology, varying image qualities captured by different microscopes and large-scale nature of neuron image datasets. A common phenomenon in the low quality neuron images is the broken structures. To tackle this problem, we propose a novel automatic 3D neuron reconstruction framework named exhaustive tracing including distance transform, optimally oriented flux filter, fast-marching and hierarchical pruning. The proposed exhaustive tracing algorithm shows a robust capability of striding over large gaps in the low quality neuron images. It outperforms state-of-the-art neuron tracing algorithms by evaluating the tracing results on the large-scale First-2000 dataset and Gold dataset.
Year
DOI
Venue
2017
10.1109/ICCVW.2017.23
2017 IEEE International Conference on Computer Vision Workshops (ICCVW)
Keywords
Field
DocType
automatic 3D single neuron reconstruction,digital reconstruction,neuronal morphology,single neurons,neuron tracing,neuronal networks,neuron image datasets,exhaustive tracing algorithm,low-quality neuron images
Iterative reconstruction,Computer vision,Pattern recognition,Computer science,Automation,Distance transform,Artificial intelligence,Digital reconstruction,Neuron,Tracing
Conference
Volume
Issue
ISSN
2017
1
2473-9936
ISBN
Citations 
PageRank 
978-1-5386-1035-0
0
0.34
References 
Authors
16
6
Name
Order
Citations
PageRank
Zihao Tang111.70
Donghao Zhang2368.73
Siqi Liu310815.57
Yang Song437953.25
Hanchuan Peng53930182.27
Weidong Cai6748.50