Title
Classification of clinical significance of MRI prostate findings using 3D convolutional neural networks.
Abstract
Prostate cancer (PCa) remains a leading cause of cancer mortality among American men. Multi-parametric magnetic resonance imaging (mpMRI) is widely used to assist with detection of PCa and characterization of its aggressiveness. Computer-aided diagnosis (CADx) of PCa in MRI can be used as clinical decision support system to aid radiologists in interpretation and reporting of mpMRI. We report on the development of a convolution neural network (CNN) model to support CADx in PCa based on the appearance of prostate tissue in mpMRI, conducted as part of the SPIE-AAPM-NCI PROSTATEx challenge. The performance of different combinations of mpMRI inputs to CNN was assessed and the best result was achieved using DWI and DCE-MRI modalities together with the zonal information of the finding. On the test set, the model achieved an area under the receiver operating characteristic curve of 0.80.
Year
DOI
Venue
2017
10.1117/12.2277123
Proceedings of SPIE
Field
DocType
Volume
Computer vision,Receiver operating characteristic,Pattern recognition,Convolutional neural network,Computer-aided diagnosis,Prostate cancer,Artificial intelligence,Clinical decision support system,Artificial neural network,Principal component analysis,Magnetic resonance imaging,Physics
Conference
10134
ISSN
Citations 
PageRank 
0277-786X
0
0.34
References 
Authors
1
10
Name
Order
Citations
PageRank
Alireza Mehrtash1445.69
Alireza Sedghi2126.80
Mohsen Ghafoorian368127.23
Mehdi Taghipour400.34
Clare M Tempany562945.11
William M. Wells III65267833.10
Tina Kapur739045.30
Parvin Mousavi836656.95
Purang Abolmaesumi9951111.52
Andriy Fedorov1017116.54