Title | ||
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Fusion of multi-parametric MRI and temporal ultrasound for characterization of prostate cancer: in vivo feasibility study. |
Abstract | ||
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Recently, multi-parametric Magnetic Resonance Imaging (mp-MRI) has been used to improve the sensitivity of detecting high-risk prostate cancer (PCa). Prior to biopsy, primary and secondary cancer lesions are identified on mp-MRI. The lesions are then targeted using TRUS guidance. In this paper, for the first time, we present a fused mp-MRI-temporal-ultrasound framework for characterization of PCa, in vivo. Cancer classification results obtained using temporal ultrasound are fused with those achieved using consolidated mp-MRI maps determined by multiple observers. We verify the outcome of our study using histopathology following deformable registration of ultrasound and histology images. Fusion of temporal ultrasound and mp-MRI for characterization of the PCa results in an area under the receiver operating characteristic curve (AUC) of 0.86 for cancerous regions with Gleason scores (GSs)>= 3+3, and AUC of 0.89 for those with GSs >= 3+4. |
Year | DOI | Venue |
---|---|---|
2016 | 10.1117/12.2217205 | Proceedings of SPIE |
Keywords | Field | DocType |
Temporal ultrasound,multi-parametric MRI,ultrasound-MRI fusion,prostate cancer | Nuclear medicine,Receiver operating characteristic,Histopathology,Biopsy,In vivo,Artificial intelligence,Prostate cancer,Computer vision,Medical physics,Cancer,Physics,Magnetic resonance imaging,Ultrasound | Conference |
Volume | ISSN | Citations |
9785 | 0277-786X | 0 |
PageRank | References | Authors |
0.34 | 0 | 19 |
Name | Order | Citations | PageRank |
---|---|---|---|
Farhad Imani | 1 | 9 | 3.44 |
Sahar Ghavidel | 2 | 5 | 1.29 |
Purang Abolmaesumi | 3 | 951 | 111.52 |
Siavash Khallaghi | 4 | 44 | 6.33 |
Eli Gibson | 5 | 188 | 23.91 |
Amir Khojaste Galesh-Khale | 6 | 28 | 4.06 |
Mena Gaed | 7 | 25 | 8.08 |
Madeleine Moussa | 8 | 27 | 8.83 |
Jose A Gomez | 9 | 43 | 7.53 |
Cesare Romagnoli | 10 | 67 | 9.65 |
Derek W. Cool | 11 | 12 | 7.56 |
matthew bastianjordan | 12 | 2 | 2.07 |
Zahra Kassam | 13 | 4 | 1.77 |
D Robert Siemens | 14 | 58 | 7.52 |
Michael Leveridge | 15 | 0 | 0.68 |
Silvia D Chang | 16 | 34 | 7.23 |
Aaron Fenster | 17 | 270 | 67.27 |
Aaron D Ward | 18 | 89 | 22.61 |
Parvin Mousavi | 19 | 366 | 56.95 |