Paper Info
Title
NGS-pipe: a flexible, easily extendable and highly configurable framework for NGS analysis.
Abstract
Motivation: Next-generation sequencing is now an established method in genomics, and massive amounts of sequencing data are being generated on a regular basis. Analysis of the sequencing data is typically performed by lab-specific in-house solutions, but the agreement of results from different facilities is often small. General standards for quality control, reproducibility and documentation are missing. Results: We developed NGS-pipe, a flexible, transparent and easy-to-use framework for the design of pipelines to analyze whole-exome, whole-genome and transcriptome sequencing data. NGSpipe facilitates the harmonization of genomic data analysis by supporting quality control, documentation, reproducibility, parallelization and easy adaptation to other NGS experiments. Availability and implementation: https://github.com/cbg-ethz/NGS-pipe Contact: niko.beerenwinkel@bsse.ethz.ch
Year
DOI
Venue
2018
10.1093/bioinformatics/btx540
BIOINFORMATICS
Field
DocType
Volume
Data mining,Transcriptome Sequencing,Computer science,Genomics,Software,Dermatology clinic,Documentation
Journal
34
Issue
ISSN
Citations 
1
1367-4803
2
PageRank 
References 
Authors
0.41
3
22
Name
Order
Citations
PageRank
Jochen Singer1182.92
Hans-Joachim Ruscheweyh220.41
Ariane L. Hofmann320.41
Thomas Thurnherr420.41
Franziska Singer541.12
Nora C. Toussaint620.41
Charlotte K. Y. Ng720.41
Salvatore Piscuoglio820.41
Christian Beisel921.09
Gerhard Christofori1020.75
Reinhard Dummer1120.75
Michael N. Hall12191.86
Wilhelm Krek1320.75
Mitchell P. Levesque1440.78
Markus G. Manz1520.75
H Moch1613115.90
Andreas Papassotiropoulos1732.17
Daniel J. Stekhoven18655.87
Peter J. Wild19314.26
Thomas Wüst2020.41
Bernd Rinn2180.92
Niko Beerenwinkel22116.13