Title | ||
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MDD-carb: a combinatorial model for the identification of protein carbonylation sites with substrate motifs. |
Abstract | ||
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This study provides a new scheme for exploring potential motif signatures at substrate sites of protein carbonylation. The usefulness of the revealed motifs in the identification of carbonylated sites is demonstrated by their effective performance in cross-validation and independent testing. Finally, these substrate motifs were adopted to build an available online resource (MDD-Carb, http://csb.cse.yzu.edu.tw/MDDCarb/ ) and are also anticipated to facilitate the study of large-scale carbonylated proteomes. |
Year | DOI | Venue |
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2017 | 10.1186/s12918-017-0511-4 | BMC Systems Biology |
Keywords | Field | DocType |
Maximal dependence decomposition,Profile hidden Markov model,Protein carbonylation,Reactive oxygen species (ROS),Substrate motifs | Substrate (chemistry),Oxidative phosphorylation,Biology,Lung disease,Cell biology,Systems biology,Protein Carbonylation,Reactive oxygen species,Computational biology,Carbonylation,Combinatorial model | Journal |
Volume | Issue | ISSN |
11 | S-7 | 1752-0509 |
Citations | PageRank | References |
1 | 0.35 | 18 |
Authors | ||
7 |
Name | Order | Citations | PageRank |
---|---|---|---|
Hui-Ju Kao | 1 | 53 | 4.59 |
Shun-Long Weng | 2 | 30 | 3.72 |
Kai-Yao Huang | 3 | 31 | 3.84 |
Fergie Joanda Kaunang | 4 | 4 | 0.86 |
Justin Bo-Kai Hsu | 5 | 108 | 6.69 |
Chien-Hsun Huang | 6 | 12 | 1.73 |
Tzong-Yi Lee | 7 | 617 | 37.18 |