Name
Title | ||
|---|---|---|
On the modeling and analysis of the biological regulatory network of NF-\({\kappa }\)B activation in HIV-1 infection. |
Abstract | ||
|---|---|---|
The complex interactions between genetic machinery of HIV-1 and host immune cells mediate dynamic adaptive responses leading to Autoimmune Deficiency Syndrome. These interactions are captured as Biological Regulatory Network (BRN) which acts to maintain the viability of host cell machinery through feedback control mechanism which is a characteristic of complex adaptive systems. In this study, the BRN of immune response against HIV-1 infection is modeled to investigate the role of NF-κB and TNF-α in disease transmission using qualitative (discrete) and hybrid modeling formalisms. |
Year | DOI | Venue |
|---|---|---|
2016 | 10.1186/s40294-015-0013-4 | CASM |
Keywords | DocType | Volume |
HIV, NF-κB, TNF-$$\alpha$$α, BRN, Qualitative modeling, Hybrid modeling | Journal | 4 |
Issue | ISSN | Citations |
1 | 2194-3206 | 3 |
PageRank | References | Authors |
0.37 | 3 | 8 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Zurah Bibi | 1 | 4 | 0.73 |
| Jamil Ahmad | 2 | 381 | 35.12 |
| Amjad Ali | 3 | 104 | 32.10 |
| Amnah Siddiqa | 4 | 5 | 1.42 |
| Shaheen Shahzad | 5 | 3 | 0.37 |
| Samar H. K. Tareen | 6 | 3 | 0.37 |
| Hussnain Ahmed Janjua | 7 | 3 | 0.37 |
| Shah Khusro | 8 | 41 | 11.92 |