Name
Title | ||
|---|---|---|
Local over-connectivity reduces the complexity of neural activity: Toward a constructive understanding of brain networks in patients with autism spectrum disorder. |
Abstract | ||
|---|---|---|
The human brain has a huge number of neurons connected to each other, forming a multitude of networks; notably, such connectivity typically exhibits a small-world structure. However, the brains of persons with autism spectrum disorder (ASD) reportedly have what has been termed as "local over-connectivity." The neural activity of the ASD brain is also atypical; resting-state EEG signals in the ASD brain have lower complexity and enhanced power at low and high frequency oscillations. In this study, we used a small-world network model based on the model proposed by Watts and Strogatz to investigate the relationship between the degree of local over-connectivity and neural activity. We controlled the degree of local over-connectivity in the model according to the parameters laid out by Watts and Strogatz. We assessed connectivity using graph-theoretical approaches, and analyzed the complexity and frequency spectrum of the activity. We found that an ASD-like network with local over-connectivity (i.e., a high clustering coefficient and a high degree of centrality) would have excessively high power in the high frequency band, and less complexity than that of a network without local over-connectivity. This result supports the idea that local over-connectivity could underlie the characteristic brain electrical activity in persons with ASD. |
Year | Venue | Field |
|---|---|---|
2017 | Joint IEEE International Conference on Development and Learning and Epigenetic Robotics ICDL-EpiRob | Neuroscience,Constructive,Frequency band,Computer science,Centrality,Human brain,Autism spectrum disorder,Clustering coefficient,Electroencephalography,Network model |
DocType | ISSN | Citations |
Conference | 2161-9484 | 0 |
PageRank | References | Authors |
0.34 | 3 | 6 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Koki Ichinose | 1 | 1 | 0.70 |
| Jihoon Park | 2 | 143 | 27.61 |
| Yuji Kawai | 3 | 9 | 6.85 |
| Junichi Suzuki | 4 | 1265 | 112.15 |
| Minoru Asada | 5 | 3147 | 561.84 |
| Hiroki Mori | 6 | 4 | 4.28 |