Name
Title | ||
|---|---|---|
Fighting Fire with Fire: Computational Prediction of Microbial Targets for Bacteriocins. |
Abstract | ||
|---|---|---|
Recently, we have witnessed the emergence of bacterial strains resistant to all known antibacterials. Due to several limitations of existing experimental methods, these events justify the need of computer-aided methods to systematically and rationally identify new antibacterial agents. Here, we propose a methodology for the systematic prediction of interactions between bacteriocins and bacterial protein targets. The protein-bacteriocin interactions are predicted using a mesh of classifiers previously developed by the authors, allowing the identification of the best bacteriocin candidates for antibiotic use and potential drug targets. |
Year | Venue | Field |
|---|---|---|
2018 | IWBBIO | Computer vision,Interactome,Support vector machine,Microbiome,Bacteriocin,Artificial intelligence,Computational biology,Engineering |
DocType | Citations | PageRank |
Conference | 0 | 0.34 |
References | Authors | |
2 | 3 | |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Edgar D. Coelho | 1 | 15 | 2.82 |
| Joel P. Arrais | 2 | 0 | 1.35 |
| José Luis Oliveira | 3 | 760 | 84.03 |