Title
A model-based control scheme for depth of hypnosis in anesthesia.
Abstract
In this paper we propose a model-based scheme to control the depth of hypnosis in anesthesia that uses the BIS signal as controlled variable. In particular, the control scheme exploits the propofol pharmacokinetics/pharmacodynamics model of the patient so that the estimated effect-site concentration is used as a feedback signal for a standard PID controller, which compensates for the model uncertainties. The tuning of the parameters is performed off-line using genetic algorithms to minimize a performance index over a given data set of patients.
Year
DOI
Venue
2018
10.1016/j.bspc.2018.01.023
Biomedical Signal Processing and Control
Keywords
Field
DocType
AEP,BIS,BIS-NADIR,DoH,EEG,IAE,PID,PD,PK,PSD,ST10,ST20,TCI,TIVA,TT,TV,US
Monte Carlo method,Performance index,PID controller,Overshoot (signal),Anesthesia,Control variable,Genetic algorithm,Mathematics,Induction Phase
Journal
Volume
ISSN
Citations 
42
1746-8094
1
PageRank 
References 
Authors
0.37
10
8