Name
Title | ||
|---|---|---|
Integrated Optical Mach-Zehnder Interferometer Based on Organic-Inorganic Hybrids for Photonics-on-a-Chip Biosensing Applications. |
Abstract | ||
|---|---|---|
The development of portable low-cost integrated optics-based biosensors for photonics-on-a-chip devices for real-time diagnosis are of great interest, offering significant advantages over current analytical methods. We report the fabrication and characterization of an optical sensor based on a Mach-Zehnder interferometer to monitor the growing concentration of bacteria in a liquid medium. The device pattern was imprinted on transparent self-patternable organic-inorganic di-ureasil hybrid films by direct UV-laser, reducing the complexity and cost production compared with lithographic techniques or three-dimensional (3D) patterning using femtosecond lasers. The sensor performance was evaluated using, as an illustrative example, E. coli cell growth in an aqueous medium. The measured sensitivity (2 x 10(-4) RIU) and limit of detection (LOD = 2 x 10(-4)) are among the best values known for low-refractive index contrast sensors. Furthermore, the di-ureasil hybrid used to produce this biosensor has additional advantages, such as mechanical flexibility, thermal stability, and low insertion losses due to fiber-device refractive index mismatch (similar to 1.49). Therefore, the proposed sensor constitutes a direct, compact, fast, and cost-effective solution for monitoring the concentration of lived-cells. |
Year | DOI | Venue |
|---|---|---|
2018 | 10.3390/s18030840 | SENSORS |
Keywords | Field | DocType |
photonic,integrated optics,sol-gel,biosensors,E. coli,organic-inorganic hybrid | Femtosecond,Mach–Zehnder interferometer,Interferometry,Chip,Electronic engineering,Engineering,Biosensor,Optoelectronics,Photonics,Fabrication,Refractive index | Journal |
Volume | Issue | Citations |
18 | 3.0 | 1 |
PageRank | References | Authors |
0.41 | 2 | 9 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| ana r n bastos | 1 | 1 | 2.10 |
| Carlos M. S. Vicente | 2 | 1 | 2.10 |
| Rui Oliveira-Silva | 3 | 1 | 0.41 |
| Nuno Silva | 4 | 67 | 9.82 |
| Marta Tacão | 5 | 1 | 0.41 |
| João P. da Costa | 6 | 1 | 0.41 |
| Mário J. S. Lima | 7 | 1 | 0.41 |
| Paulo S. André | 8 | 3 | 4.60 |
| Rute A. S. Ferreira | 9 | 1 | 3.11 |