Title
Classification Of Crystallization Outcomes Using Deep Convolutional Neural Networks
Abstract
The Machine Recognition of Crystallization Outcomes (MARCO) initiative has assembled roughly half a million annotated images of macromolecular crystallization experiments from various sources and setups. Here, state-of-the-art machine learning algorithms are trained and tested on different parts of this data set. We find that more than 94% of the test images can be correctly labeled, irrespective of their experimental origin. Because crystal recognition is key to high-density screening and the systematic analysis of crystallization experiments, this approach opens the door to both industrial and fundamental research applications.
Year
DOI
Venue
2018
10.1371/journal.pone.0198883
PLOS ONE
Field
DocType
Volume
Protein crystallization,Training set,Pattern recognition,Computer science,Convolutional neural network,Crystallization,Datasets as Topic,Artificial intelligence,Artificial neural network,Contextual image classification,Machine recognition
Journal
13
Issue
ISSN
Citations 
6
1932-6203
2
PageRank 
References 
Authors
0.54
12
8
Name
Order
Citations
PageRank
Andrew E. Bruno1294.74
Patrick Charbonneau220.54
Janet Newman321.22
Edward H. Snell420.54
David R. So522.23
Vincent Vanhoucke64735213.63
Shawn Williams720.54
Julie Wilson841.62