Title
Vectorized persistent homology representations for characterizing glandular architecture in histology images
Abstract
Characterizing glandular architecture in histology images of adenocarcinomas is a fundamental problem in digital pathology, with important implications for computer-assisted diagnosis and grading. In this paper, we present a new set of features for encoding the glandular epithelium architecture based on two recently developed vectorized persistent homology representations called persistence images and persistence landscapes and demonstrate their application to colorectal cancer diagnosis. On the MICCAI2015 Gland Segmentation Challenge Contest dataset with 165 images (85 training, 80 test images), we obtained a benign vs malignant classification accuracy of 85% and 83% using persistence image and persistence landscape based features, respectively.
Year
DOI
Venue
2018
10.1109/ISBI.2018.8363562
2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018)
Keywords
Field
DocType
Histopathology,Cancer Grading,Persistent homology,Persistence images,Persistence landscapes,Machine learning,Computer aided diagnosis
Computer vision,Architecture,Pattern recognition,Computer science,Segmentation,Computer-aided diagnosis,Digital pathology,Persistent homology,Glandular epithelium,Artificial intelligence,Histology
Conference
ISSN
ISBN
Citations 
1945-7928
978-1-5386-3637-4
0
PageRank 
References 
Authors
0.34
0
8
Name
Order
Citations
PageRank
D R Chittajallu1263.75
Neal Siekierski211.64
Sanghoon Lee374097.47
Samuel Gerber420512.82
Jonathan D. Beezley510114.55
David Manthey631.10
David A. Gutman721014.21
Lee A D Cooper812912.14