Title
Fabrication of Composite Microneedle Array Electrode for Temperature and Bio-Signal Monitoring.
Abstract
Body temperature and bio-signals are important health indicators that reflect the human health condition. However, monitoring these indexes is inconvenient and time-consuming, requires various instruments, and needs professional skill. In this study, a composite microneedle array electrode (CMAE) was designed and fabricated. It simultaneously detects body temperature and bio-signals. The CMAE consists of a 6 x 6 microneedles array with a height of 500 mu m and a base diameter of 200 mu m. Multiple insertion experiments indicate that the CMAE possesses excellent mechanical properties. The CMAE can pierce porcine skin 100 times without breaking or bending. A linear calibration relationship between temperature and voltage are experimentally obtained. Armpit temperature (35.8 degrees C) and forearm temperature (35.3 degrees C) are detected with the CMAE, and the measurements agree well with the data acquired with a clinical thermometer. Bio-signals including EII, ECG, and EMG are recorded and compared with those obtained by a commercial Ag/AgCl electrode. The CMAE continuously monitors bio-signals and is more convenient to apply because it does not require skin preparation and gel usage. The CMAE exhibits good potential for continuous and repetitive monitoring of body temperature and bio-signals.
Year
DOI
Venue
2018
10.3390/s18041193
SENSORS
Keywords
Field
DocType
microneedle array,composite electrode,body temperature,bio-signal
Biomedical engineering,Signal monitoring,Analytical chemistry,Thermometer,Voltage,Composite number,Bending,Engineering,Fabrication,Electrode,Calibration
Journal
Volume
Issue
ISSN
18
4.0
1424-8220
Citations 
PageRank 
References 
0
0.34
3
Authors
5
Name
Order
Citations
PageRank
Yiwei Sun100.34
Lei Ren267.57
Lelun Jiang300.34
Yong Tang4112.30
Bin Liu533.47